HGC or chorionic gonadotropin is a hormone produced during pregnancy. But it has been used to support weight loss as part of the HGC diet protocol.
HGC and weight loss
The use of hCG is a supplement to British endocrinologist A.T.W. Simeons’ultra-low-calorie weight-loss diet.
While studying pregnant Indian women on a calorie-deficient diet, and "fat boys" with pituitary problems, Simeons discovered that both lost fat instead of lean [muscle] tissue. He thought that, in the case of pregnant women, the HGC must be controlling the hypothalamus to do this in order to protect the developing fetus by promoting mobilization and consumption of abnormal and adipose deposits.
During his practice at the Salvador Mundi International Hospital in Rome, Italy, Simeons recommended daily low-dose HCG injections (125 mg) along with a customized ultra-low-calorie (500 cal/day, high-protein, and low-carbohydrate/fat) diet loss of adipose tissue without loss of lean tissue. He claimed that HCG could suppress appetite, burn stored fat, and even redistribute fat from the hips, thighs, and waist. However, he had no clinical evidence to back up these claims.
What studies show
There have been studies in the past which looked at HGCs weight loss abilities. However, the results were not very promising. One study even claimed that "… that there is no scientific evidence that hCG is effective in the treatment of obesity; it does not bring about weight-loss of fat-redistribution, nor does it reduce hunger or induce a feeling of well-being." (see Br J Clin Pharmacol. 1995 Sep;40(3):237-43)
In fact, HGC injections seemed to be no more effective than placebos in encouraging weight loss. When HGC was tested clinical data showed that whne you compare the results of people on a CLD or very low calorie diet [placebo group] and people on VLCD and HCG, there is no perceptible difference in weight loss and perceived hunger.
Today, HGC injections are used primarily to treat fertility problems.